7/11/2023 0 Comments Endo pain locationOCPs, progesterone-only OCPs, and medroxyprogesterone acetate (Provera) should be used as first-line therapies for treating pain associated with endometriosis.īecause gonadotropin-releasing hormone analogues provide equivalent pain relief as OCPs and progestogens with more side effects, they should be used only as second- or third-line agents. The preferred method for diagnosing endometriosis is direct visualization of lesions with histologic confirmation.ĭanazol (Danocrine) may be used for pain relief in patients with endometriosis. Hysterectomy and bilateral salpingo-oophorectomy definitively treat pain from endometriosis at 10 years in 90 percent of patients. Presacral neurectomy is particularly beneficial in women with midline pelvic pain. There is limited evidence that surgical ablation of endometriotic deposits may decrease pain and increase fertility rates in women with endometriosis. Danazol and various gonadotropin-releasing hormone analogues also are effective but may have significant side effects. Oral contraceptive pills, medroxyprogesterone acetate, and intrauterine levonorgestrel are relatively effective for pain relief. Empiric use of nonsteroidal anti-inflammatory drugs or acetaminophen is a reasonable symptomatic treatment, but the effectiveness of these agents has not been well-studied. Such diagnosis requires an experienced surgeon because the varied appearance of the disease allows less-obvious lesions to be overlooked. The preferred method for diagnosis of endometriosis is surgical visual inspection of pelvic organs with histologic confirmation. Serum markers do not provide adequate diagnostic accuracy. Signs and symptoms of endometriosis are nonspecific, and an acceptably accurate noninvasive diagnostic test has yet to be reported.
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